Anti-ADA / Adenosine deaminase Antibody
419.70 $ – 243.98 $
IHC staining of paraffin-embedded Human lung cancer tissue using ADA antibody
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Catalog No
IGX-51387
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine (PMID:8452534, PMID:16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4 (PMID:20959412). Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (PMID:11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion . Enhances CD4+ T-cell differentiation and proliferation (PMID:20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (PMID:23193172). Stimulates plasminogen activation (PMID:15016824). Plays a role in male fertility (PMID:21919946, PMID:26166670). Plays a protective role in early postimplantation embryonic development . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | ELISA: 1:1000-1:2000, WB: 1:200-1:1000, IHC: 1:25-1:100 |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human ADA |
| Specificity | ADA antibody detects endogenous level of ADA protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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