Anti-ADGRB1 Antibody
389.62 $ – 242.68 $
Immunohistochemistry of paraffin-embedded human brain tissue with rabbit anti-ADGRB1 antibody IGX-43028
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Catalog No
IGX-43028
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PMID:24509909). Also mediates the binding and engulfment of Gram-negative bacteria (PMID:26838550). Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PMID:26838550). In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PMID:24509909). Promotes myoblast fusion . Activates the Rho pathway in a G-protein-dependent manner (PMID:23782696). Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity . Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 . Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PMID:11875720). Vasculostatin-120: Inhibits angiogenesis in a CD36-dependent manner. Vasculostatin-40: Inhibits angiogenesis. |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Adhesion G protein-coupled receptor B1 protein (60-350AA) |
| Specificity | ADGRB1 antibody detects endogenous level of ADGRB1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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