Anti-AIMP1 Antibody
419.42 $ – 243.82 $
Western Blot
analysis of HeLa whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate, A549 whole cell lysate
All lanes: AIMP1 antibody at 3.7µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-50982
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase (PMID:10358004). Binds tRNA. Possesses inflammatory cytokine activity (PMID:11306575). Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation . Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels . Promotes dermal fibroblast proliferation and wound repair (PMID:16472771). Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum . Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations (PMID:12237313). Induces maturation of dendritic cells and monocyte cell adhesion (PMID:11818442). Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7 (PMID:19362550). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:200-1:500, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (25-180AA) |
| Specificity | AIMP1 antibody detects endogenous level of AIMP1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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