Anti-Anxa1 Antibody
417.46 $ – 242.68 $
Western blot
All lanes: Anxa1 antibody at 12µg/mL
Lane 1: K562 whole cell lysate
Lane 2: HeLa whole cell lysate
Lane 3: HepG2 whole cell lysate
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-48216
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PMID:12475898). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (PMID:12475898). Promotes resolution of inflammation and wound healing (PMID:25664854). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors . Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PMID:17948261). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PMID:17948261). Has no effect on unstimulated T-cells. Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton . Has high affinity for Ca2+ and can bind up to eight Ca2+ ions . Displays Ca2+-dependent binding to phospholipid membranes . Plays a role in the formation of phagocytic cups and phagosomes (PMID:21245195). Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton (PMID:21245195). |
| Host Species | Rabbit |
| Species Reactivity | Mouse, Human |
| Applications | ELISA, WB |
| Recommended Dilutions | WB: 1:500-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Mouse Annexin A1 protein (2-346AA) |
| Specificity | Anxa1 antibody detects endogenous level of Anxa1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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