Anti-ANXA1 Antibody
419.42 $ – 243.82 $
Western Blot
analysis of PC-3 whole cell lysate, K562 whole cell lysate, HeLa whole cell lysate, HepG2 whole cell lysate
All lanes: ANXA1 antibody at 2µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46445
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PMID:8425544). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response . Promotes resolution of inflammation and wound healing (PMID:25664854). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades (PMID:15187149, PMID:25664854). Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (PMID:15187149). Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PMID:17008549). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PMID:17008549). Has no effect on unstimulated T cells (PMID:17008549). Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration (PMID:15187149). Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton (PMID:19625660). Has high affinity for Ca2+ and can bind up to eight Ca2+ ions . Displays Ca2+-dependent binding to phospholipid membranes (PMID:2532504, PMID:8557678). Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IF, IP |
| Recommended Dilutions | WB: 1:1000-1:5000, IF: 1:50-1:200, IP: 1:200-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Annexin A1 protein (5-346AA) |
| Specificity | ANXA1 antibody detects endogenous level of ANXA1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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