Anti-ASH2L Antibody
389.62 $ – 242.68 $
Immunohistochemistry of paraffin-embedded human tonsil tissue with rabbit anti-ASH2L antibody IGX-42151
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Catalog No
IGX-42151
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Transcriptional regulator (PMID:12670868). Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters (PMID:19131338). Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates ‘Lys-4’ of histone H3, but not if the neighboring ‘Lys-9’ residue is already methylated (PMID:19556245). As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3 (PMID:19556245). May play a role in hematopoiesis (PMID:12670868). In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B (PMID:21220120, PMID:22266653). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Set1/Ash2 histone methyltransferase complex subunit ASH2 protein (329-628AA) |
| Specificity | ASH2L antibody detects endogenous level of ASH2L protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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