Anti-BAAT Antibody
419.28 $ – 243.74 $
Immunohistochemistry of paraffin-embedded human liver cancer with rabbit anti-BAAT antibody IGX-44316 at dilution 1:100.
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Catalog No
IGX-44316
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Catalyzes the amidation of bile acids (BAs) with the amino acids taurine and glycine (PMID:12810727, PMID:8034703, PMID:2037576, PMID:12239217). More than 95% of the BAs are N-acyl amidates with glycine and taurine (PMID:8034703). Amidation of BAs in the liver with glycine or taurine prior to their excretion into bile is an important biochemical event in bile acid metabolism (PMID:12810727). This conjugation (or amidation) plays several important biological roles in that it promotes the secretion of BAs and cholesterol into bile and increases the detergent properties of BAs in the intestine, which facilitates lipid and vitamin absorption (PMID:12810727). May also act as an acyl-CoA thioesterase that regulates intracellular levels of free fatty acids (PMID:12810727, PMID:8034703, PMID:12239217). In vitro, catalyzes the hydrolysis of long- and very long-chain saturated acyl-CoAs to the free fatty acid and coenzyme A (CoASH), and conjugates glycine to these acyl-CoAs (PMID:12810727). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IF |
| Recommended Dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Bile acid-CoA:amino acid N-acyltransferase protein (313-400AA) |
| Specificity | BAAT antibody detects endogenous level of BAAT protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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