Anti-BIN1 Antibody
390.54 $ – 243.25 $
Immunohistochemistry of paraffin-embedded human testis tissue with rabbit anti-BIN1 antibody IGX-42032
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Catalog No
IGX-42032
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling (PMID:24755653). Is a negative regulator of endocytosis . Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production (PMID:27179792). In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates . May be involved in the regulation of MYC activity and the control cell proliferation (PMID:8782822). Has actin bundling activity and stabilizes actin filaments against depolymerization in vitro (PMID:28893863). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Myc box-dependent-interacting protein 1 protein (414-593AA) |
| Specificity | BIN1 antibody detects endogenous level of BIN1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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