Anti-CARMIL2 Antibody
419.28 $ – 243.74 $
Western Blot
analysis of Jurkat whole cell lysate
All lanes: CARMIL2 antibody at 1:1000
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-49144
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization (PMID:26466680). Plays a role in cell protrusion formations; involved in cell polarity, lamellipodial assembly, membrane ruffling and macropinosome formations (PMID:19846667, PMID:26578515, PMID:26466680). Involved as well in cell migration and invadopodia formation during wound healing (PMID:19846667, PMID:26578515, PMID:26466680). Required for CD28-mediated stimulation of NF-kappa-B signaling, involved in naive T cells activation, maturation into T memory cells, and differentiation into T helper and T regulatory cells (PMID:27647349, PMID:27647348, PMID:28112205). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IP |
| Recommended Dilutions | WB: 1:500-1:2000, IP: 1:200-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Capping protein, Arp2/3 and myosin-I linker protein 2 protein (1136-1290AA) |
| Specificity | CARMIL2 antibody detects endogenous level of CARMIL2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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