Anti-CHD1 Antibody
391.72 $ – 243.98 $
Immunohistochemistry of paraffin-embedded human breast cancer with rabbit anti-CHD1 antibody IGX-42410
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-42410
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity . Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3 (PMID:18042460, PMID:28866611). Required for maintaining open chromatin and pluripotency in embryonic stem cells . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, ChIP |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA) |
| Specificity | CHD1 antibody detects endogenous level of CHD1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page