Anti-CLASP2 Antibody
419.42 $ – 243.82 $
Immunohistochemistry of paraffin-embedded human liver cancer with rabbit anti-CLASP2 antibody IGX-44814
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Catalog No
IGX-44814
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PMID:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PMID:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PMID:16866869, PMID:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IP |
| Recommended Dilutions | IHC: 1:20-1:200, IP: 1:200-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human CLIP-associating protein 2 protein (226-381AA) |
| Specificity | CLASP2 antibody detects endogenous level of CLASP2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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