Anti-CORO1C Antibody
391.72 $ – 243.98 $
Immunohistochemistry of paraffin-embedded human testis tissue with rabbit anti-CORO1C antibody IGX-42984
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Catalog No
IGX-42984
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays a role in directed cell migration by regulating the activation and subcellular location of RAC1 (PMID:25074804, PMID:25925950). Increases the presence of activated RAC1 at the leading edge of migrating cells (PMID:25074804, PMID:25925950). Required for normal organization of the cytoskeleton, including the actin cytoskeleton, microtubules and the vimentin intermediate filaments . Plays a role in endoplasmic reticulum-associated endosome fission: localizes to endosome membrane tubules and promotes recruitment of TMCC1, leading to recruitment of the endoplasmic reticulum to endosome tubules for fission (PMID:30220460). Endosome membrane fission of early and late endosomes is essential to separate regions destined for lysosomal degradation from carriers to be recycled to the plasma membrane (PMID:30220460). Required for normal cell proliferation, cell migration, and normal formation of lamellipodia . Required for normal distribution of mitochondria within cells . Isoform 3: Involved in myogenic differentiation. |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Coronin-1C protein (375-474AA) |
| Specificity | CORO1C antibody detects endogenous level of CORO1C protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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