Anti-CYP11A1 / Cholesterol side-chain cleavage enzyme mitochondrial Antibody
419.70 $ – 243.98 $
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human normal kidney tissue, Primary antibody: CYP11A1 antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-52868
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (PMID:21636783). Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (PMID:21636783). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (PMID:21636783). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB |
| Recommended Dilutions | ELISA: 1:1000-1:2000, WB: 1:200-1:1000 |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human CYP11A1 |
| Specificity | CYP11A1 antibody detects endogenous level of CYP11A1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page