Anti-DKK1 / Dickkopf-related protein 1 Antibody
419.70 $ – 243.98 $
IHC staining of paraffin-embedded Human liver cancer tissue
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-52996
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PMID:22000856). DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (PMID:17143291). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Recommended Dilutions | ELISA: 1:2000-1:5000, IHC: 1:25-1:100 |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human DKK1 |
| Specificity | DKK1 antibody detects endogenous level of DKK1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.70 $ – 243.98 $Buy now This product has multiple variants. The options may be chosen on the product page