Anti-DLD Antibody
418.48 $ – 243.28 $
Western Blot
analysis of HepG2 whole cell lysate, HeLa whole cell lysate, MCF-7 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, Rat liver tissue, Rat brain tissue, Rat heart tissue, Mouse heart tissue
All lanes: DLD antibody at 2µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-50242
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Lipoamide dehydrogenase is a component of the glycine cleavage system as well as an E3 component of three alpha-ketoacid dehydrogenase complexes (pyruvate-, alpha-ketoglutarate-, and branched-chain amino acid-dehydrogenase complex) (PMID:15712224, PMID:16442803, PMID:16770810, PMID:17404228, PMID:20160912, PMID:20385101). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion (PMID:29211711). A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A (PMID:29211711). In monomeric form may have additional moonlighting function as serine protease (PMID:17404228). Involved in the hyperactivation of spermatazoa during capacitation and in the spermatazoal acrosome reaction . |
| Host Species | Rabbit |
| Species Reactivity | Human, Rat, Mouse |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Dihydrolipoyl dehydrogenase, mitochondrial protein (398-495AA) |
| Specificity | DLD antibody detects endogenous level of DLD protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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