Anti-ECD Antibody
419.28 $ – 243.74 $
Western blot
All lanes: ECD antibody at 6µg/mL
Lane 1: HeLa whole cell lysate
Lane 2: U251 whole cell lysate
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Catalog No
IGX-48223
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PMID:16849563, PMID:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PMID:19919181, PMID:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PMID:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PMID:26711270). May play a role in regulation of pre-mRNA splicing (PMID:24722212). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB |
| Recommended Dilutions | WB: 1:500-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein ecdysoneless homolog protein (1-300AA) |
| Specificity | ECD antibody detects endogenous level of ECD protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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