Anti-FURIN Antibody
421.25 $ – 244.89 $
Immunohistochemistry of paraffin-embedded human kidney tissue with rabbit anti-FURIN antibody IGX-43275
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Catalog No
IGX-43275
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Ubiquitous endoprotease within constitutive secretory pathways capable of cleavage at the RX(K/R)R consensus motif (PMID:11799113, PMID:1629222, PMID:1713771, PMID:2251280, PMID:24666235, PMID:25974265, PMID:7592877, PMID:7690548, PMID:9130696). Mediates processing of TGFB1, an essential step in TGF-beta-1 activation (PMID:7737999). (Microbial infection) Probably cleaves and activates anthrax and diphtheria toxins. (Microbial infection) Required for H7N1 and H5N1 influenza virus infection probably by cleaving hemagglutinin. (Microbial infection) Able to cleave S.pneumoniae serine-rich repeat protein PsrP. |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Furin protein (520-701AA) |
| Specificity | FURIN antibody detects endogenous level of FURIN protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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