Anti-GABRB3 Antibody
419.42 $ – 243.82 $
Western Blot
analysis of HepG2 whole cell lysate
All lanes: GABRB3 antibody at 2.7µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-50502
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PMID:18514161, PMID:22303015, PMID:26950270, PMID:22243422, PMID:24909990). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PMID:25489750). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer . The alpha1/beta3/gamma2 receptor exhibits synaptogenic activity (PMID:25489750). The alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity . Functions also as histamine receptor and mediates cellular responses to histamine (PMID:18281286). Plays an important role in somatosensation and in the production of antinociception . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Gamma-aminobutyric acid receptor subunit beta-3 protein (328-450AA) |
| Specificity | GABRB3 antibody detects endogenous level of GABRB3 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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