Anti-GDF15 Antibody
419.70 $ – 243.98 $
Western blot
All lanes: GDF15 antibody at 4µg/mL
Lane 1: HepG2 whole cell lysate
Lane 2: Human placenta tissue
Lane 3: A549 whole cell lysate
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46582
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PMID:28953886, PMID:28846097, PMID:28846098, PMID:28846099, PMID:23468844, PMID:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PMID:28953886, PMID:28846097, PMID:28846098, PMID:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the ’emergency circuit’ that shapes feeding responses to stressful conditions (PMID:28953886). On hepatocytes, inhibits growth hormone signaling . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Growth/differentiation factor 15 protein (198-308AA) |
| Specificity | GDF15 antibody detects endogenous level of GDF15 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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