Anti-GDF15 / Growth differentiation factor 15 Antibody
419.70 $ – 243.98 $
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: GDF15 antibody at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Catalog No
IGX-53624
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses (PMID:28953886, PMID:28846097, PMID:28846098, PMID:28846099, PMID:23468844, PMID:29046435). Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem (PMID:28953886, PMID:28846097, PMID:28846098, PMID:28846099). It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which contitutes part of the ’emergency circuit’ that shapes feeding responses to stressful conditions (PMID:28953886). On hepatocytes, inhibits growth hormone signaling . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Recommended Dilutions | ELISA: 1:1000-1:5000, WB: 1:200-1:1000 |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human GDF15 |
| Specificity | GDF15 antibody detects endogenous level of GDF15 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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