Anti-GLRA1 Antibody
417.46 $ – 242.68 $
Western Blot
analysis of HepG2 whole cell lysate, A549 whole cell lysate
All lanes: GLRA1 antibody at 2.7µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-50571
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Glycine receptors are ligand-gated chloride channels (PMID:23994010, PMID:25730860). Channel opening is triggered by extracellular glycine (PMID:2155780, PMID:7920629, PMID:14551753, PMID:16144831, PMID:22715885, PMID:22973015, PMID:25973519, PMID:9009272). Channel opening is also triggered by taurine and beta-alanine (PMID:16144831, PMID:9009272). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization (PMID:14551753). Plays an important role in the down-regulation of neuronal excitability (PMID:8298642, PMID:9009272). Contributes to the generation of inhibitory postsynaptic currents (PMID:25445488). Channel activity is potentiated by ethanol (PMID:25973519). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Glycine receptor subunit alpha-1 protein (23-113AA) |
| Specificity | GLRA1 antibody detects endogenous level of GLRA1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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