Anti-GRK2 Antibody
393.17 $ – 244.89 $
Western blot
All lanes: ADRBK1 antibody at 3µg/mL + Mouse brain tissue
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Catalog No
IGX-47710
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them (PMID:19715378). Key regulator of LPAR1 signaling (PMID:19306925). Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor (PMID:19306925). Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner (PMID:19306925). Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and the stimulation of SMO activity . Inhibits relaxation of airway smooth muscle in response to blue light (PMID:30284927). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Recommended Dilutions | WB: 1:200-1:1000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Beta-adrenergic receptor kinase 1 protein (440-689AA) |
| Specificity | GRK2 antibody detects endogenous level of GRK2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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