Anti-IDO1 Antibody
418.43 $ – 243.25 $
Immunohistochemical staining of human cervical cancer with rabbit anti-IDO1 antibody IGX-50748
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Catalog No
IGX-50748
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Catalyzes the first and rate limiting step of the catabolism of the essential amino acid tryptophan along the kynurenine pathway (PMID:17671174). Involved in the peripheral immune tolerance, contributing to maintain homeostasis by preventing autoimmunity or immunopathology that would result from uncontrolled and overreacting immune responses (PMID:25691885). Tryptophan shortage inhibits T lymphocytes division and accumulation of tryptophan catabolites induces T-cell apoptosis and differentiation of regulatory T-cells (PMID:25691885). Acts as a suppressor of anti-tumor immunity (PMID:23103127, PMID:25157255, PMID:14502282, PMID:25691885). Limits the growth of intracellular pathogens by depriving tryptophan (PMID:25691885). Protects the fetus from maternal immune rejection (PMID:25691885). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Indoleamine 2,3-dioxygenase 1 protein (1-403AA) |
| Specificity | IDO1 antibody detects endogenous level of IDO1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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