Anti-IFIT2 Antibody
418.48 $ – 243.28 $
Western Blot
analysis of HEK293 whole cell lysate, Rat liver tissue
All lanes: IFIT2 antibody at 3µg/mL Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-51150
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2′-O-methylation of the 5′ cap. The ribose 2′-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2′-O-methylase for their mRNAs or by stealing host cap containing the 2′-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5′ triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis. |
| Host Species | Rabbit |
| Species Reactivity | Human, Rat |
| Applications | ELISA, WB, IHC, IF |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:500-1:1000, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Interferon-induced protein with tetratricopeptide repeats 2 protein (130-265AA) |
| Specificity | IFIT2 antibody detects endogenous level of IFIT2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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