Anti-KANK2 Antibody
389.62 $ – 242.68 $
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-54312
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Involved in transcription regulation by sequestering in the cytoplasm nuclear receptor coactivators such as NCOA1, NCOA2 and NCOA3 (PMID:17476305). Involved in regulation of caspase-independent apoptosis by sequestering the proapoptotic factor AIFM1 in mitochondria (PMID:22371500). Pro-apoptotic stimuli can induce its proteasomal degradation allowing the translocation of AIFM1 to the nucleus to induce apoptosis (PMID:22371500). Involved in the negative control of vitamin D receptor signaling pathway (PMID:24671081). Involved in actin stress fibers formation through its interaction with ARHGDIA and the regulation of the Rho signaling pathway (PMID:17996375, PMID:25961457). May thereby play a role in cell adhesion and migration, regulating for instance podocytes migration during development of the kidney (PMID:25961457). Through the Rho signaling pathway may also regulate cell proliferation . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | IHC, IF, ELISA |
| Recommended Dilutions | IHC: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:40000 |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide derived from the internal region of human KANK2. |
| Specificity | KANK2 antibody detects endogenous level of KANK2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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