Anti-KMT2B Antibody
419.42 $ – 243.82 $
Immunofluorescence staining of HeLa cells with rabbit anti-KMT2B antibody IGX-40728
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Catalog No
IGX-40728
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Histone methyltransferase that methylates ‘Lys-4’ of histone H3 (PMID:17707229). H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation (PMID:17707229). Plays a central role in beta-globin locus transcription regulation by being recruited by NFE2 (PMID:17707229). Plays an important role in controlling bulk H3K4me during oocyte growth and preimplantation development . Required during the transcriptionally active period of oocyte growth for the establishment and/or maintenance of bulk H3K4 trimethylation (H3K4me3), global transcriptional silencing that preceeds resumption of meiosis, oocyte survival and normal zygotic genome activation . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Histone-lysine N-methyltransferase 2B protein (145-290AA) |
| Specificity | KMT2B antibody detects endogenous level of KMT2B protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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