Anti-Ly6a Antibody
419.28 $ – 243.74 $
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Mouse skin tissue, Primary antibody: Ly6a antibody at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes
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Catalog No
IGX-54627
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. (Microbial infection) Promotes entry, likely through an enhanced virus-cell fusion process, of various viruses including HIV-1, West Nile virus, dengue virus and Zika virus (PMID:28130445). In contrast, the paramyxovirus PIV5, which enters at the plasma membrane, does not require LY6E (PMID:28130445, PMID:29610346). Mechanistically, adopts a microtubule-like organization upon viral infection and enhances viral uncoating after endosomal escape (PMID:28130445, PMID:30190477). |
| Host Species | Rabbit |
| Species Reactivity | Mouse |
| Applications | ELISA, WB |
| Recommended Dilutions | ELISA: 1:1000-1:2000, WB: 1:200-1:1000 |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of mouse Ly6a |
| Specificity | Ly6a antibody detects endogenous level of Ly6a protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.05% NaN3, 40% Glycerol |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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