Anti-MAP1LC3B / MAP LC3β Antibody
390.54 $ – 243.25 $
Immunohistochemical analysis of paraffin-embedded Rat Braintissue
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Catalog No
IGX-54684
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PMID:31006538, PMID:31006537). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Recommended Dilutions | WB: 1:1000-2000, IHC: 1:200-500 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Protein |
| Specificity | MAP1LC3B antibody detects endogenous level of MAP1LC3B protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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