Anti-MEF2C Antibody
391.24 $ – 243.68 $
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-54871
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex. Necessary for proper development of megakaryocytes and platelets and for bone marrow B-lymphopoiesis. Required for B-cell survival and proliferation in response to BCR stimulation, efficient IgG1 antibody responses to T-cell-dependent antigens and for normal induction of germinal center B-cells. May also be involved in neurogenesis and in the development of cortical architecture . Isoforms that lack the repressor domain are more active than isoform 1. |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | IHC, ELISA |
| Recommended Dilutions | IHC: 1:100-1:300, ELISA: 1:40000 |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide derived from the C-terminal region of human MEF2C. |
| Specificity | MEF2C antibody detects endogenous level of MEF2C protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Formulation | Liquid |
| Purification | Affinity Purified |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
419.18 $ – 243.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.18 $ – 243.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.18 $ – 243.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
419.18 $ – 243.68 $Buy now This product has multiple variants. The options may be chosen on the product page