Anti-MPP5 Antibody
419.42 $ – 243.82 $
Immunofluorescence staining of HeLa cells with rabbit anti-MPP5 antibody IGX-40371
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Catalog No
IGX-40371
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (PMID:16678097, PMID:25385611). Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface . Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity (PMID:27466317). Required during embryonic and postnatal retinal development . Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation and cerebellar layer organization . Plays a role in the radial and longitudinal extension of the myelin sheath in Schwann cells . May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter . Plays a role in the T-cell receptor-mediated activation of NF-kappa-B (PMID:21479189). Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton . Required for the normal polarized localization of the vesicular marker STX4 . Required for the correct trafficking of the myelin proteins PMP22 and MAG . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human MAGUK p55 subfamily member 5 protein (5-252AA) |
| Specificity | MPP5 antibody detects endogenous level of MPP5 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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