Anti-MTMR9 Antibody
418.48 $ – 243.28 $
Immunofluorescence staining of A549 cells with rabbit anti-MTMR9 antibody IGX-40772
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Catalog No
IGX-40772
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Acts as an adapter for myotubularin-related phosphatases (PMID:19038970, PMID:22647598). Increases lipid phosphatase MTMR6 catalytic activity, specifically towards phosphatidylinositol 3,5-bisphosphate and MTMR6 binding affinity for phosphorylated phosphatidylinositols (PMID:19038970, PMID:22647598). Positively regulates lipid phosphatase MTMR7 catalytic activity . Increases MTMR8 catalytic activity towards phosphatidylinositol 3-phosphate (PMID:22647598). The formation of the MTMR6-MTMR9 complex, stabilizes both MTMR6 and MTMR9 protein levels (PMID:19038970). Stabilizes MTMR8 protein levels (PMID:22647598). Plays a role in the late stages of macropinocytosis possibly by regulating MTMR6-mediated dephosphorylation of phosphatidylinositol 3-phosphate in membrane ruffles (PMID:24591580). Negatively regulates autophagy, in part via its association with MTMR8 (PMID:22647598). Negatively regulates DNA damage-induced apoptosis, in part via its association with MTMR6 (PMID:19038970, PMID:22647598). Does not bind mono-, di- and tri-phosphorylated phosphatidylinositols, phosphatidic acid and phosphatidylserine (PMID:19038970). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Myotubularin-related protein 9 protein (322-549AA) |
| Specificity | MTMR9 antibody detects endogenous level of MTMR9 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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