Anti-NAA10 Antibody
391.46 $ – 243.82 $
Western blot
All lanes: N-alpha-acetyltransferase 10 antibody at 5µg/mL + HeLa whole cell lysate
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Catalog No
IGX-50003
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Catalytic subunit of the N-terminal acetyltransferase A (NatA) complex which displays alpha (N-terminal) acetyltransferase activity (PMID:15496142, PMID:19826488, PMID:19420222, PMID:20145209, PMID:27708256, PMID:25489052, PMID:29754825). Acetylates amino termini that are devoid of initiator methionine (PMID:19420222). The alpha (N-terminal) acetyltransferase activity may be important for vascular, hematopoietic and neuronal growth and development. Without NAA15, displays epsilon (internal) acetyltransferase activity towards HIF1A, thereby promoting its degradation (PMID:12464182). Represses MYLK kinase activity by acetylation, and thus represses tumor cell migration (PMID:19826488). Acetylates, and stabilizes TSC2, thereby repressing mTOR activity and suppressing cancer development (PMID:20145209). Acetylates HSPA1A and HSPA1B at ‘Lys-77’ which enhances its chaperone activity and leads to preferential binding to co-chaperone HOPX (PMID:27708256). Acetylates HIST1H4A (PMID:29754825). Acts as a negative regulator of sister chromatid cohesion during mitosis (PMID:27422821). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:500-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human N-alpha-acetyltransferase 10 protein (161-235AA) |
| Specificity | NAA10 antibody detects endogenous level of NAA10 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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