Anti-NCOR1 Antibody
419.18 $ – 243.68 $
Immunofluorescence staining of HeLa cells with rabbit anti-NCOR1 antibody IGX-40577
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Catalog No
IGX-40577
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Mediates transcriptional repression by certain nuclear receptors (PMID:20812024). Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PMID:20812024). Mediates the NR1D1-dependent repression and circadian regulation of TSHB expression . The NCOR1-HDAC3 complex regulates the circadian expression of the core clock gene ARTNL/BMAL1 and the genes involved in lipid metabolism in the liver . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Nuclear receptor corepressor 1 protein (1770-1947AA) |
| Specificity | NCOR1 antibody detects endogenous level of NCOR1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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