Anti-Ngf Antibody
419.42 $ – 243.82 $
Immunoprecipitating Ngf in Rat heart tissue
Lane 1: Rabbit control IgG instead of anti-Ngf antibody IGX-45673 in Rat heart tissue.
For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/5000)
Lane 2: anti-Ngf antibody IGX-45673 (8µg) + Rat heart tissue (500µg)
Lane 3: Rat heart tissue (20µg)
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-45673
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival . The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro) . Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI . Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form . |
| Host Species | Rabbit |
| Species Reactivity | Rat |
| Applications | ELISA, IP |
| Recommended Dilutions | IP: 1:200-1:2000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Rat Beta-nerve growth factor protein (124-241AA) |
| Specificity | Ngf antibody detects endogenous level of Ngf protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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