Anti-NMNAT2 Antibody
419.70 $ – 243.98 $
Immunohistochemistry of paraffin-embedded human ovarian cancer with rabbit anti-NMNAT2 antibody IGX-43209
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Catalog No
IGX-43209
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Nicotinamide/nicotinate-nucleotide adenylyltransferase that acts as an axon maintenance factor . Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP (PMID:16118205, PMID:17402747). Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency (PMID:16118205, PMID:17402747). Cannot use triazofurin monophosphate (TrMP) as substrate (PMID:16118205, PMID:17402747). Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+ (PMID:16118205, PMID:17402747). For the pyrophosphorolytic activity prefers NAD+, NADH and NaAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively (PMID:16118205, PMID:17402747). Fails to cleave phosphorylated dinucleotides NADP+, NADPH and NaADP+ (PMID:16118205, PMID:17402747). Axon survival factor required for the maintenance of healthy axons: acts by delaying Wallerian axon degeneration, an evolutionarily conserved process that drives the loss of damaged axons . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2 protein (1-153AA) |
| Specificity | NMNAT2 antibody detects endogenous level of NMNAT2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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