Anti-PITRM1 Antibody
389.62 $ – 242.68 $
Western blot
All lanes: PITRM1 antibody at 2.42µg/mL
Lane 1: Mouse placenta tissue
Lane 2: A549 whole cell lysate
Lane 3: Rat gonad tissue
Lane 4: Mouse kidney tissue
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46806
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Metalloendopeptidase of the mitochondrial matrix that functions in peptide cleavage and degradation rather than in protein processing (PMID:10360838, PMID:16849325, PMID:19196155, PMID:24931469). Has an ATP-independent activity (PMID:16849325). Specifically cleaves peptides in the range of 5 to 65 residues (PMID:19196155). Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference (PMID:10360838, PMID:19196155, PMID:24931469). Degrades the transit peptides of mitochondrial proteins after their cleavage (PMID:19196155). Also degrades other unstructured peptides (PMID:19196155). It is also able to degrade amyloid-beta protein 40, one of the peptides produced by APP processing, when it accumulates in mitochondrion (PMID:16849325, PMID:24931469). It is a highly efficient protease, at least toward amyloid-beta protein 40 (PMID:24931469). Cleaves that peptide at a specific position and is probably not processive, releasing digested peptides intermediates that can be further cleaved subsequently (PMID:24931469). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Presequence protease, mitochondrial protein (758-1037AA) |
| Specificity | PITRM1 antibody detects endogenous level of PITRM1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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