Anti-PLA2G16 Antibody
417.46 $ – 242.68 $
Immunohistochemistry of paraffin-embedded human small intestine tissue with rabbit anti-PLA2G16 antibody IGX-41052
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-41052
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Exhibits both phospholipase A1/2 and acyltransferase activities (PMID:19615464, PMID:19047760, PMID:22825852, PMID:22605381, PMID:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PMID:19615464, PMID:19047760, PMID:22825852, PMID:22605381, PMID:22923616). For most substrates, PLA1 activity is much higher than PLA2 activity (PMID:19615464). Shows O-acyltransferase activity,catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (PMID:19615464). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE), which serves as precursor for N-acylethanolamines (NAEs) (PMID:19615464, PMID:19047760, PMID:22825852, PMID:22605381). Exhibits high N-acyltransferase activity and low phospholipase A1/2 activity (PMID:22825852). (Microbial infection) Acts as a host factor for picornaviruses: required during early infection to promote viral genome release into the cytoplasm (PMID:28077878). May act as a cellular sensor of membrane damage at sites of virus entry, which relocalizes to sites of membrane rupture upon virus unfection (PMID:28077878). Facilitates safe passage of the RNA away from LGALS8, enabling viral genome translation by host ribosome (PMID:28077878). May also be involved in initiating pore formation, increasing pore size or in maintaining pores for genome delivery (PMID:28077878). The lipid-modifying enzyme activity is required for this process (PMID:28077878). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human HRAS-like suppressor 3 protein (1-132AA) |
| Specificity | PLA2G16 antibody detects endogenous level of PLA2G16 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
417.46 $ – 242.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
417.46 $ – 242.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
417.46 $ – 242.68 $Buy now This product has multiple variants. The options may be chosen on the product page -
417.46 $ – 242.68 $Buy now This product has multiple variants. The options may be chosen on the product page