Anti-POGLUT1 Antibody
419.28 $ – 243.74 $
Western Blot
analysis of HepG2 whole cell lysate, PC-3 whole cell lysate, K562 whole cell lysate, 293 whole cell lysate
All lanes: POGLUT1 antibody at 1:2000
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-47630
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Dual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PMID:21081508, PMID:21490058, PMID:21949356, PMID:27807076, PMID:28775322). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PMID:21081508, PMID:21490058, PMID:21949356, PMID:27807076, PMID:28775322). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (PMID:27807076). Notch glucosylation does not affect Notch ligand binding (PMID:21490058). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:200-1:500 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein O-glucosyltransferase 1 protein (132-392AA) |
| Specificity | POGLUT1 antibody detects endogenous level of POGLUT1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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