Anti-PPM1D Antibody
393.17 $ – 244.89 $
Western blot
All lanes: PPM1Dantibody at 2.66µg/mL
Lane 1: Rat gonadal tissue
Lane 2: U87 whole cell lysate
Lane 3: 293T whole cell lysate
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46740
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Involved in the negative regulation of p53 expression (PMID:23242139). Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates ‘Ser-15’ of TP53 and ‘Ser-345’ of CHEK1 which contributes to the functional inactivation of these proteins (PMID:15870257, PMID:16311512). Mediates MAPK14 dephosphorylation and inactivation (PMID:21283629). Is also an important regulator of global heterochromatin silencing and critical in maintaining genome integrity . |
| Host Species | Rabbit |
| Species Reactivity | Human, Rat |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein phosphatase 1D protein (1-250AA) |
| Specificity | PPM1D antibody detects endogenous level of PPM1D protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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