Anti-PPP1R16B Antibody
418.43 $ – 243.25 $
Immunohistochemistry of paraffin-embedded human lung tissue with rabbit anti-PPP1R16B antibody IGX-41619
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Catalog No
IGX-41619
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PMID:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PMID:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity . Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage . Involved in the regulation of endothelial cell filopodia extension . May be a downstream target for TGF-beta1 signaling cascade in endothelial cells (PMID:16263087, PMID:18586956). Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation (PMID:18586956). Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1 (PMID:16263087). Involved in the dephosphorylation of EEF1A1 (PMID:26497934). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein phosphatase 1 regulatory inhibitor subunit 16B protein (101-400AA) |
| Specificity | PPP1R16B antibody detects endogenous level of PPP1R16B protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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