Anti-PTPN11 Antibody
419.18 $ – 243.68 $
Western Blot
analysis of HEK293 whole cell lysate, Mouse liver tissue, Mouse lung tissue
All lanes: PTPN11 antibody at 2.8µg/mL
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-49247
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus (PMID:10655584, PMID:18559669, PMID:18829466, PMID:26742426, PMID:28074573). Positively regulates MAPK signal transduction pathway (PMID:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PMID:28074573). Dephosphorylates ROCK2 at ‘Tyr-722’ resulting in stimulation of its RhoA binding activity (PMID:18559669). Dephosphorylates CDC73 (PMID:26742426). Dephosphorylates SOX9 on tyrosine residues, leading to inactivate SOX9 and promote ossification . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Recommended Dilutions | WB: 1:500-1:5000 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Tyrosine-protein phosphatase non-receptor type 11 protein (246-520AA) |
| Specificity | PTPN11 antibody detects endogenous level of PTPN11 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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