Anti-PTPN4 Antibody
390.58 $ – 243.28 $
Immunohistochemistry of paraffin-embedded human kidney tissue with rabbit anti-PTPN4 antibody IGX-43100
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Catalog No
IGX-43100
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PMID:25825441, PMID:27246854). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (PMID:20086240). Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction (PMID:25825441). Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway . May act at junctions between the membrane and the cytoskeleton. |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Tyrosine-protein phosphatase non-receptor type 4 protein (1-240AA) |
| Specificity | PTPN4 antibody detects endogenous level of PTPN4 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions ( provided antibody remains sterile). |
Target Gene
NA
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