Anti-RAB3IP Antibody
418.43 $ – 243.25 $
Immunohistochemistry of paraffin-embedded human kidney tissue with rabbit anti-RAB3IP antibody IGX-44336 at dilution 1:100.
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Catalog No
IGX-44336
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B (PMID:12221131, PMID:26824392). Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form (PMID:12221131, PMID:26824392). Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5 (PMID:20937701, PMID:26824392). Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface (PMID:12221131). Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (PMID:20890297). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IF |
| Recommended Dilutions | IHC: 1:20-1:200, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Rab-3A-interacting protein (1-132AA) |
| Specificity | RAB3IP antibody detects endogenous level of RAB3IP protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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