Anti-RANBP2 Antibody
418.48 $ – 243.28 $
Immunohistochemistry of paraffin-embedded human gastric cancer with rabbit anti-RANBP2 antibody IGX-41072
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Catalog No
IGX-41072
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | E3 SUMO-protein ligase which facilitates SUMO1 and SUMO2 conjugation by UBE2I (PMID:11792325, PMID:12032081, PMID:15378033, PMID:22194619, PMID:15931224). Involved in transport factor (Ran-GTP, karyopherin)-mediated protein import via the F-G repeat-containing domain which acts as a docking site for substrates (PMID:7775481). Binds single-stranded RNA (in vitro) (PMID:7775481). May bind DNA (PMID:7775481). Component of the nuclear export pathway (PMID:10078529). Specific docking site for the nuclear export factor exportin-1 (PMID:10078529). Sumoylates PML at ‘Lys-490’ which is essential for the proper assembly of PML-NB (PMID:22155184). Recruits BICD2 to the nuclear envelope and cytoplasmic stacks of nuclear pore complex known as annulate lamellae during G2 phase of cell cycle (PMID:20386726). Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity (PMID:20676357, PMID:23353830). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC |
| Recommended Dilutions | IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human E3 SUMO-protein ligase RanBP2 protein (2601-2802AA) |
| Specificity | RANBP2 antibody detects endogenous level of RANBP2 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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