Anti-RASGRP1 Antibody
417.46 $ – 242.68 $
Immunofluorescence staining of HepG2 cells with rabbit anti-RASGRP1 antibody IGX-40387
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Catalog No
IGX-40387
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP (PMID:15899849, PMID:23908768, PMID:27776107, PMID:29155103). Activates the Erk/MAP kinase cascade (PMID:15899849). Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras (PMID:10807788, PMID:12839994, PMID:27776107, PMID:29155103). Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways (PMID:19933860). Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses. May also function in differentiation of other cell types (PMID:12845332). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human RAS guanyl-releasing protein 1 protein (594-716AA) |
| Specificity | RASGRP1 antibody detects endogenous level of RASGRP1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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