Anti-RB1CC1 Antibody
418.43 $ – 243.25 $
Immunofluorescence staining of PC-3 cells with rabbit anti-RB1CC1 antibody IGX-40440
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Catalog No
IGX-40440
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Involved in autophagy (PMID:21775823). Regulates early events but also late events of autophagosome formation through direct interaction with Atg16L1 (PMID:23392225). Required for the formation of the autophagosome-like double-membrane structure that surrounds the Salmonella-containing vacuole (SCV) during S.typhimurium infection and subsequent xenophagy . Involved in repair of DNA damage caused by ionizing radiation, which subsequently improves cell survival by decreasing apoptosis . Inhibits PTK2/FAK1 and PTK2B/PYK2 kinase activity, affecting their downstream signaling pathways (PMID:10769033, PMID:12221124). Plays a role as a modulator of TGF-beta-signaling by restricting substrate specificity of RNF111 . Functions as a DNA-binding transcription factor (PMID:12095676). Is a potent regulator of the RB1 pathway through induction of RB1 expression (PMID:14533007). Plays a crucial role in muscular differentiation (PMID:12163359). Plays an indispensable role in fetal hematopoiesis and in the regulation of neuronal homeostasis . |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human RB1-inducible coiled-coil protein 1 protein (1544-1594AA) |
| Specificity | RB1CC1 antibody detects endogenous level of RB1CC1 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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