Anti-RD3 Antibody
417.46 $ – 242.68 $
Western blot
All lanes: RD3 antibody at 0.5µg/mL
Lane 1: Mouse thymus tissue
Lane 2: Human placenta tissue
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46642
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Plays a critical role in the regulation of enzymes involved in nucleotide cycle in photoreceptors (PMID:29515371, PMID:21928830, PMID:21078983, PMID:27471269, PMID:30559291). Inhibits the basal catalytic activity and the GCAP-stimulated activity of GUCY2D and GUCY2F, two retinal guanylyl cyclases involved in the production of cGMP in photoreceptors (PMID:21928830, PMID:27471269, PMID:29515371, PMID:30559291). Involved in the transport of GUCY2D and GUCY2F to their target sites in the photoreceptor outer segment (PMID:21078983). Up-regulates the activity of GUK1, a kinase that plays also an essential role for recycling GMP and indirectly, cGMP (PMID:29515371). Plays an important role for the survival of rods and cones in the retina . |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Protein RD3 protein (1-195AA) |
| Specificity | RD3 antibody detects endogenous level of RD3 protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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