Anti-RRAGC Antibody
390.58 $ – 243.28 $
Western blot
All lanes: RRAGC antibody at 1.14µg/mL
Lane 1: HeLa whole cell lysate
Lane 2: MCF-7 whole cell lysate
Lane 3: A549 whole cell lysate
Shipping cost plus VAT not included , delivery in 7-14 business days
Catalog No
IGX-46876
Supplier
ImuGeX
Size
100 μL < 50 μL
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade (PMID:20381137, PMID:27234373, PMID:24095279). Forms heterodimeric Rag complexes with RRAGA or RRAGB and cycles between an inactive GTP-bound and an active GDP-bound form (PMID:24095279). In its active form participates in the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB (PMID:20381137, PMID:27234373, PMID:24095279). This is a crucial step in the activation of the TOR signaling cascade by amino acids (PMID:20381137, PMID:27234373, PMID:24095279). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, WB, IHC |
| Recommended Dilutions | WB: 1:1000-1:5000, IHC: 1:20-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Ras-related GTP-binding protein C protein (1-250AA) |
| Specificity | RRAGC antibody detects endogenous level of RRAGC protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | Concentration can vary between different batches. |
| Storage Buffer | Phosphate-buffered saline (pH 7.3) containing 0.02% Sodium Azide (NaN3) and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains sodium azide (NaN3) as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
Related Products
-
418.48 $ – 243.28 $Buy now This product has multiple variants. The options may be chosen on the product page -
418.48 $ – 243.28 $Buy now This product has multiple variants. The options may be chosen on the product page -
418.48 $ – 243.28 $Buy now This product has multiple variants. The options may be chosen on the product page -
418.48 $ – 243.28 $Buy now This product has multiple variants. The options may be chosen on the product page