Anti-SCN9A Antibody
417.46 $ – 242.68 $
Immunohinstochemical staining with rabbit anti-SCN9A antibody IGX-45201 at 1:300 in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Catalog No
IGX-45201
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PMID:7720699, PMID:17167479, PMID:25240195, PMID:26680203, PMID:15385606, PMID:16988069, PMID:17145499, PMID:19369487, PMID:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PMID:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PMID:17167479, PMID:17145499, PMID:19369487, PMID:24311784). Activity regulationi Inhibited by tetrodotoxin (PMID:23077250). Weakly inhibited by saxitoxin (PMID:23077250). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IHC, IF |
| Recommended Dilutions | IHC: 1:200-1:500, IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Sodium channel protein type 9 subunit alpha protein (1849-1988AA) |
| Specificity | SCN9A antibody detects endogenous level of SCN9A protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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