Anti-SEMA4D Antibody
419.70 $ – 243.98 $
Immunofluorescence staining of MCF-7 cells with rabbit anti-SEMA4D antibody IGX-40610
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Catalog No
IGX-40610
Supplier
ImuGeX
Size
100 μg < 50 μg
Product Overview
Product Properties
Target Gene
Product Overview
| Description | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PMID:20877282). Regulates GABAergic synapse development . Promotes the development of inhibitory synapses in a PLXNB1-dependent manner . Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PMID:19788569). Promotes the migration of cerebellar granule cells (PMID:16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PMID:8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PMID:16055703). |
| Host Species | Rabbit |
| Species Reactivity | Human |
| Applications | ELISA, IF |
| Recommended Dilutions | IF: 1:50-1:200 |
| Conjugate | Unconjugated |
| Immunogen | Recombinant Human Semaphorin-4D protein (756-862AA) |
| Specificity | SEMA4D antibody detects endogenous level of SEMA4D protein |
Product Properties
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Clonality | Polyclonal |
| Isotype | IgG |
| Clone ID | |
| Concentration | 1 mg/mL |
| Storage Buffer | Phosphate-buffered saline (pH 7.4) containing 0.03% Proclin and 50% Glycerol. |
| Formulation | Liquid |
| Purification | This antibody is immunogen affinity purified. |
| Handling | This product contains Proclin as preservative, please take appropriate care when handling this product. |
| Reactivity Life | 12 months when stored properly according to instructions (provided antibody remains sterile). |
Target Gene
NA
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